BDBM50632583 CHEMBL5403297

SMILES [H][C@@]12CCC[C@@]1([H])OCc1cc(Nc3cc(NC)c4ncc(C(=O)N2)n4n3)c2nnn(c2c1)C([2H])([2H])[2H]

InChI Key InChIKey=SXYCXSLUFMWJMT-BMSJAHLVSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50632583   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632583(CHEMBL5403297)
Affinity DataKd:  0.00200nMAssay Description:Binding affinity to TYK2 JH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632583(CHEMBL5403297)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of TYK2 signal transduction pathway in human PBMC cells assessed as IFNalpha induced p-STAT5 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed