BDBM50631772 CHEMBL5400169

SMILES C[C@H]1CNC(=O)c2ncn3ccc(N[C@H](C)c4cc(F)ccc4O1)nc23

InChI Key InChIKey=ZPDUZRKQTNYYQZ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50631772   

TargetHigh affinity nerve growth factor receptor(Human)
University of Arkansas

Curated by ChEMBL
LigandPNGBDBM50631772(CHEMBL5400169)
Affinity DataIC50: 0.533nMAssay Description:Inhibition of His-tagged human recombinant wild type TRKAMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
University of Arkansas

Curated by ChEMBL
LigandPNGBDBM50631772(CHEMBL5400169)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of His-tagged human recombinant TRKA G595R mutantMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNT-3 growth factor receptor(Human)
University of Arkansas

Curated by ChEMBL
LigandPNGBDBM50631772(CHEMBL5400169)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of His-tagged human recombinant TRKC G623R mutantMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNT-3 growth factor receptor(Human)
University of Arkansas

Curated by ChEMBL
LigandPNGBDBM50631772(CHEMBL5400169)
Affinity DataIC50: 0.211nMAssay Description:Inhibition of His-tagged human recombinant wild type TRKCMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
University of Arkansas

Curated by ChEMBL
LigandPNGBDBM50631772(CHEMBL5400169)
Affinity DataIC50: 64nMAssay Description:Inhibition of TRKA G667C mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
University of Arkansas

Curated by ChEMBL
LigandPNGBDBM50631772(CHEMBL5400169)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant TRKA G595R mutantMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
University of Arkansas

Curated by ChEMBL
LigandPNGBDBM50631772(CHEMBL5400169)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of N-terminal His-tagged human recombinant wild type TRKAMore data for this Ligand-Target Pair
In DepthDetails
PubMed