BDBM50631769 CHEMBL5434272

SMILES OCCN1CCN(CC1)c1ccc2Nc3nccc(n3)-c3cccc(COC\C=C\COCc1c2)c3

InChI Key InChIKey=WFFGKDZTGGLZGQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50631769   

TargetTyrosine-protein kinase JAK1(Human)
University of Arkansas

Curated by ChEMBL
LigandPNGBDBM50631769(CHEMBL5434272)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human recombinant JAK1More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK2(Human)
University of Arkansas

Curated by ChEMBL
LigandPNGBDBM50631769(CHEMBL5434272)
Affinity DataIC50: 84nMAssay Description:Inhibition of human recombinant JAK2More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK3(Human)
University of Arkansas

Curated by ChEMBL
LigandPNGBDBM50631769(CHEMBL5434272)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant JAK3More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Arkansas

Curated by ChEMBL
LigandPNGBDBM50631769(CHEMBL5434272)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant FLT3 in human MV4-11 cells assessed as reduction in ERK phosphorylation by Western blotting analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 2(Human)
University of Arkansas

Curated by ChEMBL
LigandPNGBDBM50631769(CHEMBL5434272)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human recombinant CDK2 by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
University of Arkansas

Curated by ChEMBL
LigandPNGBDBM50631769(CHEMBL5434272)
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant TYK2More data for this Ligand-Target Pair
In DepthDetails
PubMed