BDBM50631768 CHEMBL5429085

SMILES COc1ccc-2cc1COC\C=C\COCc1cc(Nc3nccc-2n3)ccc1OCCN1CCCC1

InChI Key InChIKey=HLNMMXYNDBSAPI-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50631768   

TargetTyrosine-protein kinase JAK1(Human)
University of Arkansas

Curated by ChEMBL
LigandPNGBDBM50631768(CHEMBL5429085)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant JAK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
University of Arkansas

Curated by ChEMBL
LigandPNGBDBM50631768(CHEMBL5429085)
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant JAK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
University of Arkansas

Curated by ChEMBL
LigandPNGBDBM50631768(CHEMBL5429085)
Affinity DataIC50: 890nMAssay Description:Inhibition of human recombinant JAK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Arkansas

Curated by ChEMBL
LigandPNGBDBM50631768(CHEMBL5429085)
Affinity DataIC50: 92nMAssay Description:Inhibition of recombinant FLT3 in human MV4-11 cells assessed as reduction in ERK phosphorylation by Western blotting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
University of Arkansas

Curated by ChEMBL
LigandPNGBDBM50631768(CHEMBL5429085)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CDK2 by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
University of Arkansas

Curated by ChEMBL
LigandPNGBDBM50631768(CHEMBL5429085)
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant TYK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed