BDBM50631615 CHEMBL5430648

SMILES CO[C@H]1C[C@](C1)(C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C#C)c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=JVNLFPWMMSUWBB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50631615   

TargetLegumain(Human)
Roche Innovation Center Basel

Curated by ChEMBL
LigandPNGBDBM50631615(CHEMBL5430648)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant AEP (unknown origin) using Z0AAn-Rh110 as peptide substrate measured for 15 to 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetLegumain(Human)
Roche Innovation Center Basel

Curated by ChEMBL
LigandPNGBDBM50631615(CHEMBL5430648)
Affinity DataIC50: 75nMAssay Description:Inhibition of AEP (unknown origin) expressed in HEK293-A cells using fluorogenic substrate assessed as fluorescence emission intensity preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed