BDBM50631610 CHEMBL5417499

SMILES NC(=O)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)C1(CC1)c1cnn(Cc2ccccc2)c1Cl)C#C

InChI Key InChIKey=HOWRBFNZCAZGMX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50631610   

TargetLegumain(Human)
Roche Innovation Center Basel

Curated by ChEMBL
LigandPNGBDBM50631610(CHEMBL5417499)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant AEP (unknown origin) using Z0AAn-Rh110 as peptide substrate measured for 15 to 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetLegumain(Human)
Roche Innovation Center Basel

Curated by ChEMBL
LigandPNGBDBM50631610(CHEMBL5417499)
Affinity DataIC50: 98nMAssay Description:Inhibition of AEP (unknown origin) expressed in HEK293-A cells using fluorogenic substrate assessed as fluorescence emission intensity preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed