BDBM50631434 CHEMBL5412725

SMILES Nc1ccccc1NC(=O)c1ccc(CNC(=O)OC2CCCCC2)cc1

InChI Key InChIKey=UXXOYONVZZWOBK-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50631434   

TargetHistone deacetylase 1(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50631434(CHEMBL5412725)
Affinity DataIC50: 903nMAssay Description:Inhibition of HDAC1 (unknown origin) using 6-carboxyfluorescein peptide as substrate preincubated with compound followed by substrate addition by ele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50631434(CHEMBL5412725)
Affinity DataIC50: 64nMAssay Description:Inhibition of HDAC1 (unknown origin) using 6-carboxyfluorescein peptide as substrate preincubated with compound for 6 hrs followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50631434(CHEMBL5412725)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HDAC2 (unknown origin) using 6-carboxyfluorescein peptide as substrate preincubated with compound followed by substrate addition by ele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50631434(CHEMBL5412725)
Affinity DataIC50: 490nMAssay Description:Inhibition of HDAC2 (unknown origin) using 6-carboxyfluorescein peptide as substrate preincubated with compound for 2 hrs followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50631434(CHEMBL5412725)
Affinity DataIC50: 274nMAssay Description:Inhibition of HDAC2 (unknown origin) using 6-carboxyfluorescein peptide as substrate preincubated with compound for 6 hrs followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50631434(CHEMBL5412725)
Affinity DataIC50: 273nMAssay Description:Inhibition of full length recombinant human HDAC3 expressed in Sf9 cells using 6-carboxyfluorescein peptide as substrate preincubated with compound f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50631434(CHEMBL5412725)
Affinity DataIC50: 73nMAssay Description:Inhibition of full length recombinant human HDAC3 expressed in Sf9 cells using 6-carboxyfluorescein peptide as substrate preincubated with compound f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50631434(CHEMBL5412725)
Affinity DataIC50: 36nMAssay Description:Inhibition of full length recombinant human HDAC3 expressed in Sf9 cells using 6-carboxyfluorescein peptide as substrate preincubated with compound f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50631434(CHEMBL5412725)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length recombinant human HDAC8 expressed in Sf9 cells using 6-carboxyfluorescein peptide as substrate preincubated with compound f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed