BDBM50631308 CHEMBL5413283

SMILES CNC(=O)c1cnc2[nH]ccc2c1N[C@H]1CCN(Cc2ccc(nc2)C#N)[C@@H](C)C1

InChI Key InChIKey=ZUDFOFBHPJHVPB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50631308   

TargetTyrosine-protein kinase JAK1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631308(CHEMBL5413283)
Affinity DataIC50: 0.577nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed