BDBM50631307 CHEMBL5393770

SMILES CNC(=O)c1cnc2[nH]ccc2c1N[C@@H]1CCN(Cc2cnc(nc2)C(F)(F)F)[C@H](C)C1

InChI Key InChIKey=IODIOFWAUHHSJM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50631307   

TargetTyrosine-protein kinase JAK1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50631307(CHEMBL5393770)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr by TR-FRET Lanthascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed