BDBM50631111 CHEMBL5437537

SMILES COc1ccc2SCCN(CCCCNCCCCC3(O)CC3)Cc2c1

InChI Key InChIKey=JSGRFGDVHWUSTI-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50631111   

TargetRyanodine receptor 2(Homo sapiens)
Max Planck Institute for Multidisciplinary Sciences

Curated by ChEMBL
LigandPNGBDBM50631111(CHEMBL5437537)
Affinity DataEC50:  8.17E+3nMAssay Description:Modulator activity at wild type RyR2 (unknown origin) expressed in HEK293T co-expressed with R-CEPIA1er assessed as decrease in RyR2-mediated calcium...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 2(Mouse)
Max Planck Institute for Multidisciplinary Sciences

Curated by ChEMBL
LigandPNGBDBM50631111(CHEMBL5437537)
Affinity DataEC50:  2.20E+3nMAssay Description:Activation of SERCA2a in mouse HL-1 cells assessed as increase in caffeine-induced calcium release incubated for 2 hrs by FLIPR Calcium 6 dye based c...More data for this Ligand-Target Pair
In DepthDetails
PubMed