BDBM50631096 CHEMBL5401062

SMILES CN1CCN(CCCNC(=O)c2cnc(Nc3ccc4C(=O)NC(C)(C)c4c3)nc2N[C@H](CO)c2ccccc2)CC1

InChI Key InChIKey=RAUWBZBPTPSUJT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50631096   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50631096(CHEMBL5401062)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant HPK1 (1 to 346 residues) expressed in baculovirus-infected Sf9 cells using myelin basic protein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed