BDBM50631013 CHEMBL5424495

SMILES Oc1ccc(cc1C(=O)c1cnc2cc(nn2c1)-c1ccc(Cl)cc1)[N+]([O-])=O

InChI Key InChIKey=YFTLJCSWWTWMRX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50631013   

TargetRNA demethylase ALKBH5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50631013(CHEMBL5424495)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of ALKBH5 (66 to 292 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) using 5'-ATTGTCA(m6A)CAGCAGA-FAM-3' as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50631013(CHEMBL5424495)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of FTO (32 to 505 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed