BDBM50630756 CHEMBL5410824
SMILES Cc1ccc(-c2ncc3N([C@H]4CC[C@H](O)CC4)C(=O)[C@]4(C)COCCN4c3n2)c2cc[nH]c12
InChI Key InChIKey=BYZCGCXGJTYMTH-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50630756
Affinity DataIC50: 12nMAssay Description:Inhibition of mTORC2 in human PC-3 cells assessed as AKT phosphorylation at S473 residue in incubated for 1 hr by Alphascreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human GST-tagged mTOR (1360 to 2549 residues) expressed in insect cells using GFP-4E-BP1 as substrate incubated for 30 min ...More data for this Ligand-Target Pair