BDBM50630755 CHEMBL5420465

SMILES C[C@@]12COCCN1c1nc(ncc1N([C@H]1CC[C@H](O)CC1)C2=O)-c1cccc2[nH]ccc12

InChI Key InChIKey=OYXPDKVBMCFEJF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50630755   

TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50630755(CHEMBL5420465)
Affinity DataIC50: 13nMAssay Description:Inhibition of mTORC2 in human PC-3 cells assessed as AKT phosphorylation at S473 residue in incubated for 1 hr by Alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTarget of rapamycin complex subunit LST8(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50630755(CHEMBL5420465)
Affinity DataIC50: 6nMAssay Description:Inhibition of TORC1 in human PC-3 cells assessed as reduction in S6K phosphorylation at T389 residueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed