BDBM50630623 CHEMBL5438435

SMILES CCCCN(Cc1ccc(cc1)C(=O)NO)C(=O)CCCC

InChI Key InChIKey=RUZXVBRXLWFADZ-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50630623   

TargetHistone deacetylase 6(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50630623(CHEMBL5438435)
Affinity DataIC50: 32nMAssay Description:Inhibition of full length N-terminal GST-tagged human recombinant HDAC6 (1 to 1215 residues) expressed in Sf9 cells using ZMAL as fluorogenic substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50630623(CHEMBL5438435)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of full length C-terminal 6His/FLAG-tagged human recombinant HDAC1 (1 to 482 residues) purified as tubulin complex expressed in Sf9 cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50630623(CHEMBL5438435)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of full length C-terminal FLAG-tagged human recombinant HDAC2 (1 to 488 residues) expressed in Sf9 cells using ZMAL as fluorogenic substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50630623(CHEMBL5438435)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of C-terminal His-tagged human recombinant HDAC3 (1 to 428 residues)/N-terminal GST tagged human NcoR2 (395 to 489 residues) expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed