BDBM50630279 CHEMBL5422378

SMILES CCCCCCCCCCC[C@H](CC(=O)NCCO[C@@H]1O[C@H](CO)[C@@H](OS(O)(=O)=O)[C@@H](NC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCC)[C@H]1NC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCC)OC(=O)CCCCCCCCC

InChI Key InChIKey=HVGPBVPBRHMVEH-UHFFFAOYSA-N

Data  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50630279   

TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630279(CHEMBL5422378)
Affinity DataEC50:  449nMAssay Description:Agonist activity at human TLR4 in human HEK-Blue hTLR4 cells assessed as NF-kappaB activation incubated for 48 hrs by SEAP reporter gene based Quanti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Mouse)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630279(CHEMBL5422378)
Affinity DataEC50:  0.310nMAssay Description:Agonist activity at TLR4 in mouse RAW264.7 cells assessed as induction of MIP-1beta release incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Mouse)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630279(CHEMBL5422378)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at mouse TLR4 in human HEK-Blue mTLR4 cells assessed as NF-kappaB activation incubated for 48 hrs by SEAP reporter gene based Quanti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630279(CHEMBL5422378)
Affinity DataEC50:  40nMAssay Description:Agonist activity at TLR4 in human MONO-MAC-6 cells assessed as induction of MIP-1beta release incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630279(CHEMBL5422378)
Affinity DataEC50:  2.90nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of MIP-1beta release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630279(CHEMBL5422378)
Affinity DataEC50:  116nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of TNFalpha release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630279(CHEMBL5422378)
Affinity DataEC50:  20nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of IL-1beta release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630279(CHEMBL5422378)
Affinity DataEC50:  7nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of RANTES release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed