BDBM50630275 CHEMBL5417929

SMILES CCCCCCCCCCCCCC(=O)O[C@@H](CCCCCCCCCCC)CC(=O)N[C@H]1[C@H](OC[C@H]2O[C@H](O)[C@H](NC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](OC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H]2O)O[C@H](CO)[C@@H](OP(O)(O)=O)[C@@H]1OC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC

InChI Key InChIKey=JSNQJZJCKAFSHT-UHFFFAOYSA-N

Data  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50630275   

TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630275(CHEMBL5417929)
Affinity DataEC50:  6.20nMAssay Description:Agonist activity at human TLR4 in human HEK-Blue hTLR4 cells assessed as NF-kappaB activation incubated for 48 hrs by SEAP reporter gene based Quanti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Mouse)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630275(CHEMBL5417929)
Affinity DataEC50:  0.490nMAssay Description:Agonist activity at TLR4 in mouse RAW264.7 cells assessed as induction of MIP-1beta release incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Mouse)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630275(CHEMBL5417929)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at mouse TLR4 in human HEK-Blue mTLR4 cells assessed as NF-kappaB activation incubated for 48 hrs by SEAP reporter gene based Quanti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630275(CHEMBL5417929)
Affinity DataEC50:  0.990nMAssay Description:Agonist activity at TLR4 in human MONO-MAC-6 cells assessed as induction of MIP-1beta release incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630275(CHEMBL5417929)
Affinity DataEC50:  0.760nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of MIP-1beta release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630275(CHEMBL5417929)
Affinity DataEC50:  10nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of TNFalpha release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630275(CHEMBL5417929)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of IL-1beta release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Inimmune

Curated by ChEMBL
LigandPNGBDBM50630275(CHEMBL5417929)
Affinity DataEC50:  1.90nMAssay Description:Agonist activity at TLR4 in human PBMC cells assessed as induction of RANTES release incubated for 20 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed