BDBM50630023 CHEMBL5411178

SMILES [3H]CC([3H])C(=O)N[C@H](CCCC[C@@H](N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O

InChI Key InChIKey=QJZDTDUMJIUCEP-BEBOKERVSA-N

Data  3 KI  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50630023   

TargetNeuropeptide Y receptor type 4(Homo sapiens)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50630023(CHEMBL5411178)
Affinity DataKd:  0.670nMAssay Description:Binding affinity to human Y4R under sodium free conditionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50630023(CHEMBL5411178)
Affinity DataKd:  9.80nMAssay Description:Binding affinity to human Y4R under 140 mM sodium conditionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50630023(CHEMBL5411178)
Affinity DataKi:  0.390nMAssay Description:Displacement of [3H]-(9S,12S,15S,19R,E)-4-amino-N-((S)-1-(((S)-1-(((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl)amino)-5-guanidino-1-oxopentan-2-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50630023(CHEMBL5411178)
Affinity DataKi:  0.870nMAssay Description:Binding affinity to human Y4R under hypotonic sodium free conditionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50630023(CHEMBL5411178)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]-(9S,12S,15S,19R,E)-4-amino-N-((S)-1-(((S)-1-(((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl)amino)-5-guanidino-1-oxopentan-2-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed