BDBM50629779 CHEMBL5438762

SMILES CNc1ncnc2n(cnc12)[C@@H]1O[C@H](CNS(=O)(=O)c2ccc(OC)c(c2)C#N)[C@@H](O)[C@H]1O

InChI Key InChIKey=ZTSMMYJPTKWLLM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50629779   

TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50629779(CHEMBL5438762)
Affinity DataIC50: 468nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV 2 nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50629779(CHEMBL5438762)
Affinity DataIC50: 3.99E+3nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50629779(CHEMBL5438762)
Affinity DataIC50: 5.62E+4nMAssay Description:Inhibition of N-terminal 6His-tagged human RNMT activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA and [3H]-SAM as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed