BDBM50629550 CHEMBL5437751

SMILES Cc1ccccc1C(=O)Nc1cnc(Nc2cccc(N)c2)nc1

InChI Key InChIKey=HAEFJVPMEPTGPH-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50629550   

TargetTyrosine-protein kinase Blk(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50629550(CHEMBL5437751)
Affinity DataEC50: >30nMAssay Description:Induction of ubiquitin proteasomal system dependent BLK degradation in human Ramos cells measured after 12 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein kinase Blk(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50629550(CHEMBL5437751)
Affinity DataIC50: 480nMAssay Description:Inhibition of N-terminal GST tagged BLK (1 to 505 end residues) (unknown origin) expressed in Sf21insect cells by time resolved fluorescence based as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed