BDBM50629539 CHEMBL5409793

SMILES CN(C)C\C=C\C(=O)N1CCC(CC1)c1cccc(Nc2ncc(NC(=O)c3cc(NC(=O)c4ccc5cnccc5c4)ccc3C)cn2)c1

InChI Key InChIKey=YOWWKNUFWIKCQG-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50629539   

TargetTyrosine-protein kinase Blk(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50629539(CHEMBL5409793)
Affinity DataEC50:  12nMAssay Description:Induction of ubiquitin proteasomal system dependent BLK degradation in human Ramos cells measured after 12 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein kinase Blk(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50629539(CHEMBL5409793)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of N-terminal GST tagged BLK (1 to 505 end residues) (unknown origin) expressed in Sf21insect cells by time resolved fluorescence based as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed