BDBM50629127 CHEMBL5412556

SMILES NC(=O)CN(NC(=O)[C@@H]1CCCN1C(=O)C1(CC1)c1ccc(OC(F)(F)F)cc1)C(=O)CCl

InChI Key InChIKey=NOCMYTLPYXINQD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50629127   

TargetLegumain(Human)
Roche Innovation Center Basel

Curated by ChEMBL
LigandPNGBDBM50629127(CHEMBL5412556)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant AEP (unknown origin) using Z0AAn-Rh110 as peptide substrate measured for 15 to 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetLegumain(Human)
Roche Innovation Center Basel

Curated by ChEMBL
LigandPNGBDBM50629127(CHEMBL5412556)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human 8His-tagged AEP (V18 to Y433 residues) using Z-Ala-Ala-Asn-Rhl 10-(D-Pro) as substrate incubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed