BDBM50629104 CHEMBL5417620

SMILES COc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCN(CC1)C(=S)SCC(=O)N1CCN(CC1)C1CCCC1)N1CCOCC1

InChI Key InChIKey=POVXOIDMYNXYMG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50629104   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629104(CHEMBL5417620)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of N-terminal GST-fused full-length human PI3Kalpha (1 to 1068 residues) expressed in baculovirus expression system using PIP2 as substrat...More data for this Ligand-Target Pair
In DepthDetails
PubMed