BDBM50628429 CHEMBL5402698

SMILES Fc1ccc(Cc2n[nH]c(=O)c3ccccc23)cc1C(=O)N1CCn2c(C1)nnc2-c1ccc(Br)o1

InChI Key InChIKey=STSCRAGBCYODMY-UHFFFAOYSA-N

Data  16 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50628429   

TargetPoly [ADP-ribose] polymerase 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50628429(CHEMBL5402698)
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50628429(CHEMBL5402698)
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50628429(CHEMBL5402698)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of PARP7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50628429(CHEMBL5402698)
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of PARP1 (unknown origin) using histone as substrate by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50628429(CHEMBL5402698)
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of PARP2 (unknown origin) using histone as substrate by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP3(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50628429(CHEMBL5402698)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PARP3 (unknown origin) using biotinylated NAD+ as substrate by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP4(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50628429(CHEMBL5402698)
Affinity DataIC50: 1nMAssay Description:Inhibition of PARP4 (unknown origin) using biotinylated NAD+ as substrate by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50628429(CHEMBL5402698)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of PARP5A (unknown origin) using biotinylated NAD+ as substrate by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50628429(CHEMBL5402698)
Affinity DataIC50: 12nMAssay Description:Inhibition of PARP5B (unknown origin) using biotinylated NAD+ as substrate by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50628429(CHEMBL5402698)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of PARP6 (unknown origin) using biotinylated NAD+ as substrate by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50628429(CHEMBL5402698)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of PARP7 (unknown origin) using biotinylated NAD+ as substrate by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50628429(CHEMBL5402698)
Affinity DataIC50: 11nMAssay Description:Inhibition of PARP10 (unknown origin) using biotinylated NAD+ as substrate by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50628429(CHEMBL5402698)
Affinity DataIC50: 2.17E+3nMAssay Description:Inhibition of PARP11 (unknown origin) using biotinylated NAD+ as substrate by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP12(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50628429(CHEMBL5402698)
Affinity DataIC50: 14nMAssay Description:Inhibition of PARP12 (unknown origin) using biotinylated NAD+ as substrate by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50628429(CHEMBL5402698)
Affinity DataIC50: 3.59E+4nMAssay Description:Inhibition of PARP14 (unknown origin) using biotinylated NAD+ as substrate by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP15(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50628429(CHEMBL5402698)
Affinity DataIC50: 5.16E+4nMAssay Description:Inhibition of PARP15 (unknown origin) using biotinylated NAD+ as substrate by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed