BDBM50627913 CHEMBL5435354

SMILES O[C@H](CCN1CCC(Cc2ccccc2)CC1)c1ccc2[nH]ncc2c1

InChI Key InChIKey=DLLHDEONAMMACT-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50627913   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
University Munster

Curated by ChEMBL
LigandPNGBDBM50627913(CHEMBL5435354)
Affinity DataIC50: 62nMAssay Description:Antagonist activity at GluN2B receptor (unknown origin) expressed in Xenopus oocytes coexpressing GluN1a at -70 mV holding potential in presence of (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University Munster

Curated by ChEMBL
LigandPNGBDBM50627913(CHEMBL5435354)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane assessed as inhibition constant measured after 120 mins by sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSigma intracellular receptor 2(Rat)
University Munster

Curated by ChEMBL
LigandPNGBDBM50627913(CHEMBL5435354)
Affinity DataKi:  241nMAssay Description:Displacement of [3H]di-o-tolylguanidine from sigma2 receptor in rat liver membrane assessed as inhibition constant measured after 120 mins by scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
University Munster

Curated by ChEMBL
LigandPNGBDBM50627913(CHEMBL5435354)
Affinity DataKi:  265nMAssay Description:Displacement of [3H]ifenprodil from human GluN2B expressed in mouse L-M(TK-) cell membrane coexpressing GluN1a assessed as inhibition constant measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed