BDBM50627878 CHEMBL5402803

SMILES CCCC[C@H](NC(=O)[C@@H](NC(=O)CNC(C)=O)C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(N)=O

InChI Key InChIKey=HFTWJOGNIDLGNZ-UHFFFAOYSA-N

Data  3 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50627878   

TargetHistone-lysine N-methyltransferase NSD2(Human)
University of Texas Medical Branch (UTMB)

Curated by ChEMBL
LigandPNGBDBM50627878(CHEMBL5402803)
Affinity DataKd:  3.00E+3nMAssay Description:Binding affinity to GST-tagged human NSD2 assessed as dissociation assMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone-lysine N-methyltransferase NSD2(Human)
University of Texas Medical Branch (UTMB)

Curated by ChEMBL
LigandPNGBDBM50627878(CHEMBL5402803)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of NSD2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
University of Texas Medical Branch (UTMB)

Curated by ChEMBL
LigandPNGBDBM50627878(CHEMBL5402803)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of NSD3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone-lysine N-methyltransferase NSD2(Human)
University of Texas Medical Branch (UTMB)

Curated by ChEMBL
LigandPNGBDBM50627878(CHEMBL5402803)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of WHSC1 (941 to 1240 residues) (unknown origin) using biotinylated-RLARRGGVKRISGLI as substrate incubated for 120 mins in presence of [3H...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone-lysine N-methyltransferase NSD2(Human)
University of Texas Medical Branch (UTMB)

Curated by ChEMBL
LigandPNGBDBM50627878(CHEMBL5402803)
Affinity DataKd:  3.00E+3nMAssay Description:Binding affinity to Avi-tagged WHSC1 (941 to 1240 residues) (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed