BDBM50627697 CHEMBL5412274
SMILES CCCN1CCOc2cccc(C[C@H](NC(=O)c3cccc(c3)C1=O)[C@H](O)CNC(C)(C)c1cccc(OC)c1)c2
InChI Key InChIKey=AZASRRIQYBSWGO-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50627697
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis
Curated by ChEMBL
Latvian Institute of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 6.80nMAssay Description:Inhibition of recombinant Plasmodium falciparum 3D7 PMX using DABCYLHSFIQEGKEE-EDANS as fluorogenic substrate incubated for 5 mins followed by substr...More data for this Ligand-Target Pair
TargetPlasmepsin IV(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis
Curated by ChEMBL
Latvian Institute of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of Plasmodium falciparum PMIV using DABCYL-ERNIeFLSFP-EDAN as substrate preincubated for 20 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of human CatD using DABCYL-ERNIeFLSFP-EDAN as substrate preincubated for 20 mins followed by substrate addition and measured after 20 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of human BACE1 using E-EDANS-EVNLDAEFK-DABCYL-R as substrate preincubated for 20 mins followed by substrate addition and measured after 60...More data for this Ligand-Target Pair