BDBM50627692 CHEMBL5400043
SMILES COc1cccc(c1)C(C)(C)NC[C@@H](O)[C@@H]1Cc2cccc(OCCCCN(C)C(=O)c3cccc(c3)C(=O)N1)c2
InChI Key InChIKey=KMZTVKCJBGRXHN-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50627692
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis
Curated by ChEMBL
Latvian Institute of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Inhibition of recombinant Plasmodium falciparum 3D7 PMX using DABCYLHSFIQEGKEE-EDANS as fluorogenic substrate incubated for 5 mins followed by substr...More data for this Ligand-Target Pair
TargetPlasmepsin IV(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis
Curated by ChEMBL
Latvian Institute of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of Plasmodium falciparum PMIV using DABCYL-ERNIeFLSFP-EDAN as substrate preincubated for 20 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of human CatD using DABCYL-ERNIeFLSFP-EDAN as substrate preincubated for 20 mins followed by substrate addition and measured after 20 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of human BACE1 using E-EDANS-EVNLDAEFK-DABCYL-R as substrate preincubated for 20 mins followed by substrate addition and measured after 60...More data for this Ligand-Target Pair