BDBM50627489 CHEMBL5438158
SMILES FC12CC3CC(C1)CC(C3)(C2)NC1=N\C(=C/c2ccc3ncsc3c2)C(=O)N1
InChI Key InChIKey=QIYXLIZWXGGKOO-UHFFFAOYSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50627489
Affinity DataIC50: 7nMAssay Description:Inhibition of N-terminal GST/His6-fused human full length CLK1 (1 to 484 residues) expressed in Sf9 cells assessed as inhibition of autophosphorylati...More data for this Ligand-Target Pair
Affinity DataIC50: 0nMAssay Description:Inhibition of human CLK2 using GSK3(14-27) peptide and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 194nMAssay Description:Inhibition of human full length CLK3 (1 to 490 residues) expressed in Sf9 cells using S6 peptide and [gamma33P]ATP as substrate incubated for 60 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Perha Pharmaceuticals
Curated by ChEMBL
Perha Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0nMAssay Description:Inhibition of human DYRK1A using RBERCHKtide and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
Perha Pharmaceuticals
Curated by ChEMBL
Perha Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0nMAssay Description:Inhibition of human DYRK1B using RBERCHKtide and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Perha Pharmaceuticals
Curated by ChEMBL
Perha Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human DYRK2 using RBERIRStide and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 3(Human)
Perha Pharmaceuticals
Curated by ChEMBL
Perha Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human DYRK3 using RBERIRStide and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 4(Human)
Perha Pharmaceuticals
Curated by ChEMBL
Perha Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of human DYRK4 using RBERCHKtide and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 169nMAssay Description:Inhibition of N-terminal GST/His6-fused human full length GSK-3-beta (1 to 420 residues) expressed in Sf9 cells using RBERCHKtide and [gamma33P]ATP a...More data for this Ligand-Target Pair
Affinity DataIC50: 612nMAssay Description:Inhibition of human CK1 epsilon using casein and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Perha Pharmaceuticals
Curated by ChEMBL
Perha Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 146nMAssay Description:Inhibition of N-terminal GST/His6-fused human full length CDK5 (1 to 292 residues)/N-terminal His6-fused human p25 (104 to 307 residues) coexpressed ...More data for this Ligand-Target Pair