BDBM50627193 CHEMBL5394656

SMILES Cc1nn(C)c-2c1CSCc1cc(CCc3cc(OCCCc4c(C([O-])=O)n(C)c5c-2c(Cl)ccc45)c2ccccc2c3)n(C)n1

InChI Key

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50627193   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50627193(CHEMBL5394656)
Affinity DataKi:  0.0320nMAssay Description:Displacement of Cy5-labeled BIM BH3 peptide (H3N-(C/Cy5Mal)-WIAQELRRIGDEFN-OH) from MCL-1 (unknown origin) assessed as inhibition constant incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed