BDBM50627097 CHEMBL5441034

SMILES CN1CCC(CC1)NC(=O)OCC#Cc1cc(F)c(OCc2nnc(S[C@@H]3CCCC=C3)n2-c2cccnc2)cc1F

InChI Key InChIKey=YBCFFJLDKVTSPF-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50627097   

TargetTransitional endoplasmic reticulum ATPase(Human)
University of Pittsburgh Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50627097(CHEMBL5441034)
Affinity DataIC50: 12nMAssay Description:Inhibition of p97 (unknown origin) ATPase activity by Biomol Green Reagent based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTransitional endoplasmic reticulum ATPase(Human)
University of Pittsburgh Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50627097(CHEMBL5441034)
Affinity DataEC50:  230nMAssay Description:Inhibition of p97 in human HeLa cells expressing UbG76V-GFP/ODD-Luc assessed as accumulation of Ub-GFP incubated for 6 hrs by confocal microscopic an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed