BDBM50626601 CHEMBL5430344
SMILES CC[C@H]1N(C2CCCC2)c2nc(Nc3ccc(cc3OC)-c3noc(CN4CCNCC4)n3)ncc2N(C)C1=O
InChI Key InChIKey=CQQFCBITQKNHPX-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50626601
TargetSerine/threonine-protein kinase PLK1(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 0.450nMAssay Description:Inhibition of PLK1 (unknown origin) preincubated for 10 mins followed by substrate addition measured after 60 mins in presence of ATP by ADP-Glo assa...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK2(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 5.70nMAssay Description:Inhibition of PLK2 (unknown origin) preincubated for 10 mins followed by substrate addition measured after 60 mins in presence of ATP by ADP-Glo assa...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK3(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 7.60nMAssay Description:Inhibition of PLK3 (unknown origin) preincubated for 10 mins followed by substrate addition measured after 60 mins in presence of ATP by ADP-Glo assa...More data for this Ligand-Target Pair
Affinity DataIC50: 156nMAssay Description:Inhibition of BRD4 (unknown origin) using BET peptide as substrate incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair