BDBM50625247 CHEMBL5414244

SMILES Nc1ccccc1NC(=O)\C=C\c1ccc(NC(=O)Cc2ccc3ccccc3c2)cn1

InChI Key InChIKey=ISUGSSCHUUDEPF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50625247   

TargetHistone deacetylase 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50625247(CHEMBL5414244)
Affinity DataIC50: 203nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic p53 (379-382 residues) (RHKK(Ac)AMC) as substrateMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50625247(CHEMBL5414244)
Affinity DataIC50: 414nMAssay Description:Inhibition of human recombinant HDAC3 using fluorogenic p53 (379-382 residues) (RHKK(Ac)AMC) as substrateMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50625247(CHEMBL5414244)
Affinity DataIC50: 7.71E+4nMAssay Description:Inhibition of human recombinant HDAC8 using fluorogenic diacetylated p53 (379-382 residues) (RHKK(Ac)K(Ac)AMC) as substrateMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed