BDBM50624544 CHEMBL5439993
SMILES Oc1c(Cl)cc(cc1Cl)C(=O)n1ccc2cccnc12
InChI Key InChIKey=HVYNCNZJQZOKFM-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50624544
Affinity DataIC50: 800nMAssay Description:Inhibition of human URAT1 stably overexpressing in human HEK293 cells assessed as inhibition of 14C-uric acid uptake preincubated for 30 mins followe...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetSolute carrier family 2, facilitated glucose transporter member 9(Mus musculus)
Southern Medical University
Curated by ChEMBL
Southern Medical University
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mouse GLUT9 transfected in human HEK293 cells assessed as inhibition of uric acid induced current by cell patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of OAT1 (unknown origin) transfected in HEK293 cells assessed as inhibition of 6-CFL uptake preincubated for 30 mins followed by 6-CFL add...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Southern Medical University
Curated by ChEMBL
Southern Medical University
Curated by ChEMBL
Affinity DataIC50: 4.04E+3nMAssay Description:Inhibition of ABCG2 (unknown origin) transfected in HEK293 cell membrane vesicle assessed as inhibition of 14C-uric acid uptake incubated for 15 mins...More data for this Ligand-Target Pair
Ligand InfoSimilars