BDBM50623925 CHEMBL5426374

SMILES CS(=O)(=O)N1CC[C@@H](C1)C#CC(=O)N1CCC[C@H](C1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=OUPVMVHXMWBFDP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50623925   

TargetTyrosine-protein kinase JAK1(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50623925(CHEMBL5426374)
Affinity DataIC50: 32nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50623925(CHEMBL5426374)
Affinity DataIC50: 32nMAssay Description:Inhibition of TYK2 signalling pathway in human PBMC cells assessed as IFN alpha induced p-STAT1 levelMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50623925(CHEMBL5426374)
Affinity DataIC50: 46nMAssay Description:Inhibition of TYK2 signalling pathway in human PBMC cells assessed as IFN alpha induced p-STAT3 levelMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed