BDBM50623116 CHEMBL5416999
SMILES COc1ccc2Nc3nccc(n3)-c3cccc(COC\C=C\COCc1c2)c3
InChI Key InChIKey=NVVRIZGTMNCPSN-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50623116
Affinity DataIC50: 70nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human recombinant JAK1More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant JAK2More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant JAK3More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant FLT3 in human MV4-11 cells assessed as reduction in ERK phosphorylation by Western blotting analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 860nMAssay Description:Inhibition of human recombinant CDK2 by Kinomescan methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 210nMAssay Description:Inhibition of human recombinant TYK2More data for this Ligand-Target Pair
Ligand InfoSimilars