BDBM50622457 CHEMBL5419652
SMILES Fc1ccc(cc1)-c1ccncc1NC(=O)c1ccnc(Nc2ccc(cc2)C#N)n1
InChI Key InChIKey=QLWFPXXGZGCHFQ-UHFFFAOYSA-N
Data 27 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 27 hits for monomerid = 50622457
TargetAurora kinase A(Mouse)
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of mouse Aurora kinase AMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetInterleukin-1 receptor-associated kinase 1(Human)
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of IRAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetInsulin-like growth factor 1 receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of IGF1R (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetMast/stem cell growth factor receptor Kit(Human)
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of c-Kit (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetCasein kinase II subunit alpha'(Human)
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CK2A2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetCasein kinase II subunit alpha(Human)
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CK2A1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetTyrosine-protein kinase BTK(Human)
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetAurora kinase B(Human)
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Aurora kinase B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetAP2-associated protein kinase 1(Human)
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of AAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of GSK-3 in human U2OS cells transfected with beta-catenin GFP and 4R1N tau plasmid assessed as inhibition of Tau phosphorylation at Ser39...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetGlycogen synthase kinase-3 alpha(Human)
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:Displacement of FL-KRREILSRRP[ps]ERYR-NH2 from human recombinant full length GST-tagged GSK-3-alpha expressed in insect cells incubated for 20 hrs by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetGlycogen synthase kinase-3 beta(Human)
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Affinity DataIC50: 0.350nMAssay Description:Displacement of FL-KRREILSRRP[ps]ERYR-NH2 from human recombinant N-terminal His6-tagged GSK-3-beta (14 to 306 residues) H355L mutant expressed in bac...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetMAP kinase-activated protein kinase 2(Human)
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of MK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetMitogen-activated protein kinase 14(Human)
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of MAPK p38-alpha (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetCasein kinase I isoform alpha(Human)
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CK1A1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetSerine/threonine-protein kinase pim-1(Human)
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Affinity DataIC50: 720nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetCyclin-dependent kinase 5(Human)
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of CDK5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetCyclin-dependent kinase 2(Human)
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetTyrosine-protein kinase SYK(Human)
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetRibosomal protein S6 kinase alpha-1(Human)
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of RSK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetProtein kinase C theta type(Human)
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of PKC theta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPlatelet-derived growth factor receptor beta(Human)
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of PDGFR-beta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetTyrosine-protein kinase Lck(Human)
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetTyrosine-protein kinase JAK2(Human)
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetTyrosine-protein kinase JAK1(Human)
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research and Development Center
Curated by ChEMBL
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars