BDBM50619106 CHEMBL5416914

SMILES CC(C)n1cc(cn1)-c1nc(Nc2ccc(CNC(=O)CCCl)cc2)ncc1C

InChI Key InChIKey=JALGVGXDRIKISN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50619106   

TargetTyrosine-protein kinase JAK2(Human)
The Affiliated Hospital of Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50619106(CHEMBL5416914)
Affinity DataIC50: 985nMAssay Description:Inhibition of JAK2 V617F mutant in human SET2 cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosine-protein kinase JAK2(Mouse)
The Affiliated Hospital of Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50619106(CHEMBL5416914)
Affinity DataIC50: 385nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
The Affiliated Hospital of Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50619106(CHEMBL5416914)
Affinity DataIC50: 5.56E+3nMAssay Description:Inhibition of FLT3 in human MOLM-13 cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed