BDBM50619105 CHEMBL5440964
SMILES CC(C)n1cc(cn1)-c1nc(Nc2ccc(CNC(=O)CCl)cc2)ncc1C
InChI Key InChIKey=HKUUMUKNJAIXDM-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50619105
TargetTyrosine-protein kinase JAK2(Human)
The Affiliated Hospital of Southwest Jiaotong University
Curated by ChEMBL
The Affiliated Hospital of Southwest Jiaotong University
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of JAK2 V617F mutant in human SET2 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Mouse)
The Affiliated Hospital of Southwest Jiaotong University
Curated by ChEMBL
The Affiliated Hospital of Southwest Jiaotong University
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:Inhibition of JAK2 V617F mutant in mouse BaF3 cellsMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
The Affiliated Hospital of Southwest Jiaotong University
Curated by ChEMBL
The Affiliated Hospital of Southwest Jiaotong University
Curated by ChEMBL
Affinity DataIC50: 961nMAssay Description:Inhibition of FLT3 in human MOLM-13 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Human)
The Affiliated Hospital of Southwest Jiaotong University
Curated by ChEMBL
The Affiliated Hospital of Southwest Jiaotong University
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of JAK1 (unknown origin) in presence of Mg/ATP mixture by [gamma p33]-ATP based radiometric assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Human)
The Affiliated Hospital of Southwest Jiaotong University
Curated by ChEMBL
The Affiliated Hospital of Southwest Jiaotong University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of JAK2 (unknown origin) in presence of Mg/ATP mixture by [gamma p33]-ATP based radiometric assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Human)
The Affiliated Hospital of Southwest Jiaotong University
Curated by ChEMBL
The Affiliated Hospital of Southwest Jiaotong University
Curated by ChEMBL
Affinity DataIC50: 166nMAssay Description:Inhibition of JAK3 (unknown origin) in presence of Mg/ATP mixture by [gamma p33]-ATP based radiometric assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
The Affiliated Hospital of Southwest Jiaotong University
Curated by ChEMBL
The Affiliated Hospital of Southwest Jiaotong University
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of TYK2 (unknown origin) in presence of Mg/ATP mixture by [gamma p33]-ATP based radiometric assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
The Affiliated Hospital of Southwest Jiaotong University
Curated by ChEMBL
The Affiliated Hospital of Southwest Jiaotong University
Curated by ChEMBL
Affinity DataIC50: 206nMAssay Description:Inhibition of FLT3 (unknown origin) in presence of Mg/ATP mixture by [gamma p33]-ATP based radiometric assayMore data for this Ligand-Target Pair