BDBM50618548 CHEMBL5413385

SMILES CC(C)C[C@H](NC(=O)OCC(C)(C)Oc1ccc(Cl)cc1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C=O

InChI Key InChIKey=WBJZVUPGWANLHC-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50618548   

TargetReplicase polyprotein 1ab(2019-nCoV)
Wichita State University

Curated by ChEMBL
LigandPNGBDBM50618548(CHEMBL5413385)
Affinity DataIC50: 460nMAssay Description:Inhibition of N-terminal His6-tagged full length SARS-CoV-2 3CLpro using FAM-SAVLQ as substrate preincubated with enzyme for 1 hr followed by susbtra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Wichita State University

Curated by ChEMBL
LigandPNGBDBM50618548(CHEMBL5413385)
Affinity DataIC50: 170nMAssay Description:Inhibition of N-terminal His6-tagged full length SARS-CoV-2 3CLpro using FAM-SAVLQ as substrate preincubated with enzyme for 1 hr followed by susbtra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProthrombin(Human)
Wichita State University

Curated by ChEMBL
LigandPNGBDBM50618548(CHEMBL5413385)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetChymotrypsinogen B2(Human)
Wichita State University

Curated by ChEMBL
LigandPNGBDBM50618548(CHEMBL5413385)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeutrophil elastase(Human)
Wichita State University

Curated by ChEMBL
LigandPNGBDBM50618548(CHEMBL5413385)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCathepsin B(Human)
Wichita State University

Curated by ChEMBL
LigandPNGBDBM50618548(CHEMBL5413385)
Affinity DataIC50: 800nMAssay Description:Inhibition of human Cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCathepsin D(Human)
Wichita State University

Curated by ChEMBL
LigandPNGBDBM50618548(CHEMBL5413385)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human Cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCathepsin G(Human)
Wichita State University

Curated by ChEMBL
LigandPNGBDBM50618548(CHEMBL5413385)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human Cathepsin GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProcathepsin L(Human)
Wichita State University

Curated by ChEMBL
LigandPNGBDBM50618548(CHEMBL5413385)
Affinity DataIC50: 40nMAssay Description:Inhibition of human Cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed