BDBM50618084 CHEMBL5437375

SMILES CN(c1ccc2c(C)n(C)nc2c1)c1ccnc(Nc2ccc(C)c(c2)-c2nc3c(cccc3[nH]2)C(N)=O)n1

InChI Key InChIKey=DCYHJVFMNYSPNT-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50618084   

TargetVascular endothelial growth factor receptor 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50618084(CHEMBL5437375)
Affinity DataIC50: 191nMAssay Description:Inhibition of VEGFR2 (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50618084(CHEMBL5437375)
Affinity DataIC50: 61nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50618084(CHEMBL5437375)
Affinity DataIC50: 166nMAssay Description:Inhibition of VEGFR1 (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50618084(CHEMBL5437375)
Affinity DataIC50: 499nMAssay Description:Inhibition of VEGFR3 (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50618084(CHEMBL5437375)
Affinity DataIC50: 299nMAssay Description:Inhibition of FMS (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase 16(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50618084(CHEMBL5437375)
Affinity DataIC50: 148nMAssay Description:Inhibition of MPSK1 (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50618084(CHEMBL5437375)
Affinity DataIC50: 347nMAssay Description:Inhibition of MLK3 (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase TAO2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50618084(CHEMBL5437375)
Affinity DataIC50: 689nMAssay Description:Inhibition of TAO2 (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50618084(CHEMBL5437375)
Affinity DataIC50: 78nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed