BDBM50617989 CHEMBL5401589
SMILES [H][C@]1(C[C@H](O)[C@H](C)[C@@H](O1)\C=C\C)[C@H](N)\C=C\C=C(/C)C[C@@H](C)\C=C(\C)/C=C/[C@H](O)C[C@H](N)CC(=O)OC
InChI Key InChIKey=PLLUXUKFSITXBR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50617989
Affinity DataKd: 4.60E+3nMAssay Description:Binding affinity to CRM1 (unknown origin) assessed as dissociation constant by microscale thermophoresis assayMore data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of CRM1-mediated nuclear export in human HeLa cells expressing mCherry-tagged NES reporter incubated for 3 hrs by confocal microscopy anal...More data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of CRM1 nuclear export in human HeLa cells assessed as CRM1 depletion measured after 6 hrsMore data for this Ligand-Target Pair