BDBM50617898 CHEMBL5412461

SMILES Cc1ccc(cc1)-c1c(C#N)c(=O)n(Cc2ccccc2)c2ccccc12

InChI Key InChIKey=YWCFECFIMPYNMP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50617898   

LigandPNGBDBM50617898(CHEMBL5412461)
Affinity DataIC50: 48nMAssay Description:Inhibition of PDE1C (147 to 531 residues) (unknown origin) using 3H-cGMP as substrate incubated for 15 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50617898(CHEMBL5412461)
Affinity DataIC50: 5.83E+3nMAssay Description:Inhibition of PDE9A (181 to 506 residues) (unknown origin) using 3H-cGMP as substrate incubated for 15 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed