BDBM50617608 CHEMBL5423636

SMILES Cc1nnc2CCC(Nc3ccc(Cl)cc3)c3cc(ccc3-n12)-c1ccc(CNCCCCCCCc2cccc3C(=O)N(Cc23)C2CCC(=O)NC2=O)cc1

InChI Key InChIKey=XVZADHPETCRQKA-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50617608   

TargetBromodomain-containing protein 3(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50617608(CHEMBL5423636)
Affinity DataKi:  2.30nMAssay Description:Binding affinity to recombinant human BRD3 BD2 (306 to 417 residues) assessed as inhibition constant by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetBromodomain-containing protein 3(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50617608(CHEMBL5423636)
Affinity DataKi:  7.90nMAssay Description:Binding affinity to recombinant human BRD3 BD1 (24 to 144 residues) assessed as inhibition constant by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed