BDBM50616956 CHEMBL5422418

SMILES COc1cnc(Nc2cccc(c2)S(N)(=O)=O)nc1N1CCN(C(=O)C1)c1ccccc1

InChI Key InChIKey=MHMPZSOMHQSWEN-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50616956   

TargetBone morphogenetic protein receptor type-2(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50616956(CHEMBL5422418)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of recombinant C-terminal 6His-tagged human BMPR2 (188 to 517 residues) expressed in Escherichia coli Rosetta by LanthaScreen TR-FRET assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase receptor R3(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50616956(CHEMBL5422418)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of ACVRL1 (unknown origin) by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50616956(CHEMBL5422418)
Affinity DataKi:  7nMAssay Description:Inhibition of recombinant C-terminal 6His-tagged human BMPR2 (188 to 517 residues) expressed in Escherichia coli Rosetta assessed as apparent inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed