BDBM50616787 CHEMBL5441124

SMILES FC(F)(F)Oc1ccccc1C(=O)N1CCN(CC1)C(=O)c1ccc(CNc2n[nH]c3ccccc23)cc1

InChI Key InChIKey=SMQPNHQJKKSXPI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50616787   

TargetMitogen-activated protein kinase 8(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50616787(CHEMBL5441124)
Affinity DataIC50: 8.28E+3nMAssay Description:Inhibition of JNK1 (unknown origin) using ULight-4E-BP1 peptide as substrate incubated for 90 mins in presence of ATP by Lance ultra assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50616787(CHEMBL5441124)
Affinity DataIC50: 394nMAssay Description:Inhibition of JNK3 (unknown origin) using ULight-4E-BP1 peptide as substrate incubated for 90 mins in presence of ATP by Lance ultra assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed