BDBM50616292 CHEMBL5398323

SMILES COc1cc2C(=O)N(C(=O)c2cc1CN[C@@H](CO)C(O)=O)c1cccc(c1C)-c1ccccc1

InChI Key InChIKey=CUQPAAUFONWYPW-UHFFFAOYSA-N

Data  1 IC50  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50616292   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50616292(CHEMBL5398323)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of europium-labeled PD-1/biotinylated PD-L1 interaction (unknown origin) preincubated for 15 mins with PD-L1 followed by PD-1 addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50616292(CHEMBL5398323)
Affinity DataKd:  71nMAssay Description:Binding affinity to human PD-L1 assessed as dissociation constant by MST analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50616292(CHEMBL5398323)
Affinity DataEC50:  121nMAssay Description:Inhibition of PD-1 Fc IgG fusion protein binding to PD-L1 in human NCI-H460 cells incubated for 6 hrs by DAPI/PD-1 anti-human IgG DyLight 488 stainin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed