BDBM50616111 CHEMBL5403199

SMILES Cn1cc(cn1)-c1cnc2Nc3ccc(C#N)c(CCCCOc4ccccc4[C@@H](CO)Nc1n2)c3

InChI Key InChIKey=AOJDKUXYLYKLKG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50616111   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50616111(CHEMBL5403199)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of HPK1 (unknown origin) using MBP protein as substrate in presence of ATP preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50616111(CHEMBL5403199)
Affinity DataIC50: 54nMAssay Description:Inhibition of GLK (unknown origin) using MBP protein as substrate in presence of ATP preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed