BDBM50614709 CHEMBL5273615

SMILES Cc1ccc(NC(=O)Nc2cc(cc3C(CCCOc23)c2ccccc2)-c2ccccc2-c2nc(=O)[nH]o2)cc1

InChI Key InChIKey=SQJLSONUOZSTDQ-UHFFFAOYSA-N

Data  6 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50614709   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50614709(CHEMBL5273615)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of IDO1 (unknown origin) expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50614709(CHEMBL5273615)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of IDO1 (unknown origin) expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50614709(CHEMBL5273615)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of TDO (unknown origin) expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50614709(CHEMBL5273615)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of TDO (unknown origin) expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50614709(CHEMBL5273615)
Affinity DataEC50:  5.50E+3nMAssay Description:Transactivation of PXR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50614709(CHEMBL5273615)
Affinity DataEC50:  4.20E+3nMAssay Description:Transactivation of PXR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCytochrome P450 2C19(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50614709(CHEMBL5273615)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCytochrome P450 2B6(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50614709(CHEMBL5273615)
Affinity DataIC50: 780nMAssay Description:Inhibition of CYP2B6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed