BDBM50613993 CHEMBL5286246

SMILES Cc1cc(=O)c2c(F)cncc2n1-c1c(Cl)cc(cc1Cl)C#N

InChI Key InChIKey=MLKRCEWWRVAFRU-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50613993   

TargetG protein-activated inward rectifier potassium channel 4(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50613993(CHEMBL5286246)
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant human GIRK1/4 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG protein-activated inward rectifier potassium channel 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50613993(CHEMBL5286246)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human GIRK1/2 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50613993(CHEMBL5286246)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human Nav1.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50613993(CHEMBL5286246)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human Cav1.2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50613993(CHEMBL5286246)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human KCNQ1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50613993(CHEMBL5286246)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant hERG in the presence of dofetilide by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed